A new study about tics and stimulants, published in Neurology, 2002;58:527-536:
Treatment of ADHD in children with tics: a randomized controlled trial
Treatment of ADHD in children with tics: a randomized controlled trial
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TSNowWhat |
Tics and Stimulants |
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Posts: 12126 (07/07/01 15:20:06) EZOP/Ribbit |
A new study about tics and stimulants, published in Neurology, 2002;58:527-536:
Treatment of ADHD in children with tics: a randomized controlled trial |
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TSNowWhat |
Re: Tics and Stimulants | ||
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Posts: 12126 (07/04/02 19:15:13) EZOP/Ribbit |
A comprehensive review of the pharmacologic agents currently available for the treatment and management of children with ADHD.
http://www.medscape.com/viewarticle/437026_5 While ADHD appears to be a major factor in the impairment attributed to Tourette's syndrome,[56] it is unclear whether the presence of tics has a general impact on the course of ADHD. Our group examined this issue in an ongoing prospective study of ADHD boys.[57] We found that ADHD boys had more tic disorders at baseline and follow-up than controls. However, tic disorders had little impact on the psychosocial functioning of ADHD boys, and stimulant treatment was not associated with increased rates, severity, or persistence of tic disorders. Recent studies have demonstrated that stimulants are effective in many children with ADHD and tic disorders.[58-60 ] Nonetheless, it seems prudent to weigh the risks and benefits of individual cases and to conduct appropriate discussions with the patient and family about the risks and benefits of the use of stimulants in individuals with ADHD and tics. |
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Re: Tics and Stimulants | ||
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Posts: 12126 (07/04/02 19:15:55) EZOP/Ribbit |
Tics Due to Attention Disorder, Not Drug Treatment (Medscape - dead link)
QUOTES: But a growing body of research demonstrates that tics can arise in children with ADHD whether or not they take medication. For example, a recent study found that 5% of non-medicated children with ADHD also had tic disorders, and were 60 times more likely than their peers without the attention disorder to have Tourette's syndrome. In an interview with Reuters Health, Dr. Roger Kurlan of the University of Rochester in New York, who reviewed the findings from Dr. Turgay and his team, agreed that medications are not likely to blame when children with ADHD develop tics. Rather, he explained, patients often develop tics within 1 year or 2 after they have been diagnosed with ADHD, whether or not they receive treatment. "Study after study after study is showing that medication is not part of the [tic] disorders," he said. "It's just part of the natural course of ADHD." Also available at mkadhd.org Thanks, KBurra ! |
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TSNowWhat |
Tics and Desipramine | ||
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Posts: 12126 (07/31/02 13:30:15) EZOP/Ribbit |
Desipramine Effective For Children With Tic Disorder And ADHD (Medscape - dead link)
NEW YORK (Reuters Health) Jul 16 - Desipramine effectively reduces symptoms in children with chronic tic disorder and attention-deficit/hyperactivity disorder (ADHD), according to a report in the July issue of the Archives of General Psychiatry. Desipramine treatment also significantly reduced tics, with progressive improvement during the study, the results indicate, whereas placebo had an insignificant effect on tics. "To our knowledge," the researchers write, "our findings are the first to document a statistically and clinically robust improvement of tic symptoms associated with desipramine treatment under double-blind conditions." "Our results suggest that desipramine may offer an effective alternative for the treatment of patients with chronic tics and ADHD," the authors conclude. "Additionally, desipramine offers some advantages over stimulants, including a longer duration of action obviating the need to administer medication during school hours, absence of abuse potential, and putative positive effects on mood and anxiety, and sleep." A Double-blind Comparison of Desipramine and Placebo in Children and Adolescents With Chronic Tic Disorder and Comorbid Attention-Deficit/Hyperactivity Disorder Thomas Spencer, MD; Joseph Biederman, MD; Barbara Coffey, MD; Daniel Geller, MD; Margaret Crawford, MD; Sarah Kate Bearman, BA; Reem Tarazi, BA; Stephen V. Faraone, PhD Arch Gen Psychiatry. 2002;59:649-656 Thanks KBurra ! |
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Re: Tics and Stimulants | ||
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Posts: 12126 (10/18/05 17:38:17) EZOP/Ribbit |
Tourette Syndrome: Current Controversies and the Battlefield Landscape,
Neal R Swerdlow MD PhD Department of Psychiatry, UCSD School of Medicine Current Neurology and Neuroscience Reports 2005, 5:329-331 "Another controversy in TS treatment surrounds the use of stimulants, once disfavored based on reports of tic exacerbations. More recent prospective, longitudinal studies now support the safety and efficacy of stimulants in patients with comorbid TS plus ADHD, with some evidence for a reduction in tic severity in these patients. Nonetheless, based on residual lore and non-data-based concerns, stimulants may still be underused in TS patients." |
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Posts: 12126 (11/19/05 03:49:43) EZOP/Ribbit |
Tourette's Syndrome: are stimulants safe?
Treatment of ADHD in children with tics: a randomized controlled trial. Emergence of tics in children with ADHD: impact of once-daily OROS methylphenidate therapy. Ritalin is okay for kids with both ADHD and Tourette's syndrome, study says. Methylphenidate to treat ADHD is not contraindicated in children with tics. |
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Posts: 12126 (11/19/05 03:59:14) EZOP/Ribbit |
TSNW - Tics and Stimulants
TSA Statement on methylphenidate (Ritalin) and clonidine (Catapres) Roger Freeman MD on how the tics/stimulants myth came about: Tourette Syndrome: Minimizing Confusion: "Why Do Books Say That You Should Never Give a Stimulant Drug to Someone With Tics/TS? There was an observation on a few cases over 25 years ago that some children with ADHD, given a stimulant like Ritalin or Dexedrine, developed tics. This seemed to confirm some animal research showing that high doses of these drugs brought out stereotyped behaviour. For years after this publication, no one had the nerve to continue treating a person who developed tics, to see what would happen. Then drug companies were sued in the US, claiming that the childrens' TS was caused by the drug. The Scientologists picked this up and (through their "Citizens Commission on Human Rights") started warning people that if their child takes Ritalin, he/she will develop TS. To this day, the warning remains in the US and Canadian drug books, despite much clinical experience and research that shows this is not usually so. A recent study showed that roughly 22% of children taking any drug (including Ritalin) had an increase of tics temporarily. ADHD normally starts in very early childhood, so when TS followed, it was assumed that the drug was the cause; at that time TS was thought to be very rare, so something external had to be causing it. We use stimulants for concurrent ADHD fairly often, regardless of whether the child has TS, and have been doing so for years. But don't expect to see the warning removed from books any time soon!" |
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Posts: 12126 (12/04/05 14:31:08) EZOP/Ribbit |
ADHD Kids May Have Bipolar Disorder, Too
"If a child with ADHD has an undiagnosed bipolar disorder as well, conventional ADHD therapy can worsen the bipolar disorder," she tells WebMD. The typical therapy for ADHD is a stimulant such as Ritalin or Adderall. |
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Re: Tics and Stimulants | ||
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Posts: 12126 (12/13/05 18:15:00) EZOP/Ribbit |
New Treatment Options For Children With ADHD
This is an effective medicine that doctors have been told for decades not to use in children with tics, such as children with Tourettes syndrome, says lead author Roger Kurlan, M.D., a neurologist at the University of Rochester Medical Center. Theres even a warning in the Physicians Desk Reference, and for 40 years physicians have avoided treating children with ADHD and tics with Ritalin because of a fear that the tics would worsen. But the warning was based on slim evidence and had never really been checked out thoroughly. |
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